Memory Loss
# Adaptive Engram cell plasticity
Source: Forgetting as a form of adaptive engram cell plasticity
Based on theory that memories are stored in ensembles of neurons (’engram cells’) and success fo recall involves reactivation of these ensembles.
Forgetting involves circult remodelling that switches engram cells from an accessible state to an inaccessible state. Forgetting is a form of neuroplasticity that alters engram cell accessibility in a manner that is sensitive to mismatch between expectations and the environment.